PhD Students
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Maria Koch |
Queensland University of Technology
PhD Candidate
Project Title: Development of translational 3D models for breast cancer research
Project Aim: Two dimensional cultures do not recreate the dynamic and highly complex tissue microenvironment and thus are physiologically irrelevant. In situ, cells are embedded in an extracellular matrix that provides not only architectural support, but also chemical and mechanical signals to cells in vivo. This study seeks to uncover the cellular interactions in breast cancer that control its vascularisation, development and metastasis through the development of more relevant and sophisticated three dimensional culture technologies. By understanding how breast cancer develops and metastasises, we have the potential to provide novel therapeutic intervention points, streamline the testing of new drugs and individualise patient treatment strategies.
PhD Candidate
Project Title: Development of translational 3D models for breast cancer research
Project Aim: Two dimensional cultures do not recreate the dynamic and highly complex tissue microenvironment and thus are physiologically irrelevant. In situ, cells are embedded in an extracellular matrix that provides not only architectural support, but also chemical and mechanical signals to cells in vivo. This study seeks to uncover the cellular interactions in breast cancer that control its vascularisation, development and metastasis through the development of more relevant and sophisticated three dimensional culture technologies. By understanding how breast cancer develops and metastasises, we have the potential to provide novel therapeutic intervention points, streamline the testing of new drugs and individualise patient treatment strategies.
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Anna Jäschke |
Queensland University of Technology
PhD Candidate
Project Title: Development of translational 3D models for prostate cancer research
Project Aim: Two dimensional cultures do not recreate the dynamic and highly complex tissue microenvironment and thus are physiologically irrelevant. In situ, cells are embedded in an extracellular matrix that provides not only architectural support, but also chemical and mechanical signals to cells in vivo. This study seeks to uncover the cellular interactions in prostate cancer that control its vascularisation, development and metastasis through the development of more relevant and sophisticated three dimensional culture technologies. By understanding how prostate cancer develops and metastasises, we have the potential to provide novel therapeutic intervention points, streamline the testing of new drugs and individualise patient treatment strategies.
PhD Candidate
Project Title: Development of translational 3D models for prostate cancer research
Project Aim: Two dimensional cultures do not recreate the dynamic and highly complex tissue microenvironment and thus are physiologically irrelevant. In situ, cells are embedded in an extracellular matrix that provides not only architectural support, but also chemical and mechanical signals to cells in vivo. This study seeks to uncover the cellular interactions in prostate cancer that control its vascularisation, development and metastasis through the development of more relevant and sophisticated three dimensional culture technologies. By understanding how prostate cancer develops and metastasises, we have the potential to provide novel therapeutic intervention points, streamline the testing of new drugs and individualise patient treatment strategies.
